This project comprised synthesis and biological testing of potential antituberculostatics and was subject of a diploma thesis entitled "Biologically active benzoxazoles". The project included preparation of seventeen original compounds, eight Schiff bases made from 2-amino-4,6-di-tert-butylphenol and appropriate aromatic aldehydes and nine 5,7-di-tert-butylbenzoxazoles substituted in position 2 by aromatic substituents. In the introduction of the theses was presented a comprehensive review on the biological activity of benzoxazoles available from the literature. All compounds were sent for evaluation of their antituberculous activity to the laboratories in USA in a project "Tuberculosis antimicrobial acquisition and coordinating facility (TAACF)".The results of these studies that will include results from the biological testing not yet completed, will be published in a relevant international scientific journal. The results from the chemical part of this project were presented in a student research conference at the Faculty of Pharmacy and a scientific symposium "Progress in organic, bioorganic and pharmaceutical chemistry" held in Nymburk (November 26.-28.th, 2004).